发明名称 徐放性医薬組成物
摘要 Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected frommonosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.
申请公布号 JP5860406(B2) 申请公布日期 2016.02.16
申请号 JP20120538723 申请日期 2011.10.14
申请人 国立大学法人京都大学;京都府公立大学法人;科研製薬株式会社;株式会社高研 发明人 福島 雅典;松原 弘明;的場 聖明;土方 重樹;阿蘇 雄;佐藤 勉
分类号 A61K47/42;A61K9/08;A61K38/00;A61K47/26;A61P1/02;A61P9/00;A61P9/10;A61P17/02;A61P19/00;A61P35/00;A61P43/00 主分类号 A61K47/42
代理机构 代理人
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