Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids

摘要

A process for the manufacture of an ester or the respective free acid of a 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acid of formula (I), wherein in such formula (I), Y is H, F or an alkyl group having from 1 to 12 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group or an aryl group; R1 is H or an organic residue; R2 is H or an organic residue. Such process comprises submitting a compound of formula (II) to a reduction reaction, wherein in such formula (II), Y is the same as defined for formula (I); X is Cl, Br or I; R1′ is H or an organic residue; and R2′ is H or an organic residue.;

主权项

1. A process for the manufacture of an ester of a 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acid of formula (I) wherein Y is H, F or an alkyl group having from 1 to 12 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group or an aryl group, R1 is H or an organic residue, R2 is H or an organic residue, said process comprising submitting a compound of formula (II) to a reduction reaction, wherein: Y is the same as defined above for formula (I), X is Cl, Br or I, R1′ is H or an organic residue, and R2′ is H or an organic residue.