发明名称 Verfahren zur Herstellung von 5-Nitro-2-substituierten Benzimidazolen
摘要 <p>A. Process: R = a hetero aromatic 5-membered ring containing 1-3 hetero atoms such as N, -O and -S; R' = H, hydroxy, alkyl or alkoxy; B. Unspecified 2-substd.-5-aminobenzimidazoles of general formula (I) R and R1 as signified. (I) are active anthelmintics and may be used in the treatment of helminthiasis in animals. Simple process in which the 2-substd. benzimidazole cpds. are selectively nitrated at pos.5 without nitrating the substituent at pos.2 5-amino 2-(4'-thiazolyl)benzimidazole.</p>
申请公布号 CH499537(A) 申请公布日期 1970.11.30
申请号 CH19680005736 申请日期 1968.04.18
申请人 MERCK & CO., INC. 发明人 HERBERT FISHER,MICHAEL
分类号 A61K31/415;C07D239/74;C07D417/04;(IPC1-7):C07D99/02 主分类号 A61K31/415
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