Methods of treating traveler's diarrhea and hepatic encephalopathy

摘要

Treatment of traveler's diarrhea using in subjects having hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin.

主权项

1. A method of reducing the risk of overt hepatic encephalopathy (HE) recurrence in a subject comprising:
identifying a subject having Traveler's Diarrhea (TD) that also has hepatic insufficiency; determining if the subject's Child-Pugh score is Child-Pugh Class C or if the subject's model end stage liver disease (MELD) score is 25 or greater; and administering between 1000 and 1200 mg of rifaximin daily and cautiously to the subject if his or her Child-Pugh score is Child-Pugh Class C or if his or her MELD score is 25 or greater.