ADMINISTRATION REGIME FOR N-HYDROXY-4-BENZAMIDE

摘要

N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2-ylcarbonylamino]ethoxy}-benzamide of formula (I):;;or an addition salt thereof with a pharmaceutically acceptable acid or base, alone or in association with surgery, chemotherapy or hormone therapy treatment or radiotherapy, for use in the treatment of cancer, characterised in that it is administered for 4 consecutive days, that period being followed by 3 consecutive days without any administration of compound of formula (I), with the proviso that the chemotherapy is not FOLFOX.

主权项

1- A method of treating a condition selected from carcinoma, tumours, neoplasm, lymphoma, melanoma, glioma, sarcoma, and blastoma in a subject in need thereof, comprising administration of an effective amount of N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2-ylcarbonylamino]ethoxy}benzamide of formula (I):or an addition salt thereof with a pharmaceutically acceptable acid or base, alone or in combination with a surgery, chemotherapy, hormone therapy treatment, or radiotherapy.