| 摘要 |
The present invention pertains to the domain of Alzheimer's disease, and provides a new marker for evaluating the probability, for an individual, of developing the disease, as well as a diagnostic marker and a target for identifying new drugs for treating this neurodegenerative disease. In particular, the invention provides a genetic marker based on the combination of two single nucleotide polymorphisms, at positions -389 and -241 of the ornithine transcarbamylase (OTC) gene. |
