PHARMACEUTICLAL COMPOSITION FOR ANTI-TUSSIVE ACTIVITY OR DISCHARGE OF PHLEGM ACTIVITY COMPRISING EXTRACTS OF DENDROPANAX MORBIFERA

摘要

PURPOSE: A pharmaceutical composition containing a Dendropanax morbifera leaf extract is provided to ensure antitussive activity and expectoration removal without side effects using a hot water extract of Dendropanax morbifera leaves and a chloroform fraction of a Dendropanax morbifera leaf extract. CONSTITUTION: A pharmaceutical composition for antitussive activity and expectoration removal contains a Dendropanax morbifera leaf extract as an active ingredient. A crude extract of Dendropanax morbifera leaves is prepared using a solvent selected among water, methanol, ethanol, propanol, isopropanol, butanol, and a mixture thereof. The daily dose of the extract is 10-2000 mg/kg. [Reference numerals] (AA) Extract 1kg of Dendropanax morbifera leaves by hot water extraction using H2O at 100°C and dry; (BB) Sequentially fraction 249g of the hot water extract using hexane, chloroform, ethyl acetate, and butanol according to the polarity of each solvent