发明名称 |
MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF |
摘要 |
<p>The present invention provides multifunctional nitroxide derivatives comprising a potassium channel opener and a reactive oxygen species (ROS) degradation catalyst that can act as an anti-oxidant, as well as pharmaceutical compositions comprising them. The multifunctional compounds and pharmaceutical compositions of the invention are useful for treatment of diseases, disorders or conditions associated with oxidative stress or endothelial dysfunction.</p> |
申请公布号 |
CA2820763(A1) |
申请公布日期 |
2012.06.14 |
申请号 |
CA20112820763 |
申请日期 |
2011.12.08 |
申请人 |
RADIKAL THERAPEUTICS INC. |
发明人 |
JAGTAP, PRAKASH;SALZMAN, ANDREW LURIE |
分类号 |
C07D207/46;A61K31/40;A61K31/4427;A61K31/4439;A61K31/444;A61K31/4468;A61K31/55;A61P9/10;A61P25/28;A61P39/00;C07D211/94;C07D223/12;C07D401/12 |
主分类号 |
C07D207/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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