发明名称 |
NON-DIFFUSIVE BOTULINUM TOXIN CAUSING LOCAL MUSCLE PARALYSIS, AND PURIFICATION METHOD THEREOF |
摘要 |
The present invention relates to a method for purifying non-diffusive botulinum toxin causing local muscle paralysis, and non-diffusive botulinum toxin purified thereby, and more specifically, to a method for purifying non-diffusive botulinum toxin comprising the following step: treating a purified botulinum toxin type A formulation with anion chromatography in which sodium chloride (NaCl) with controlled concentration is added, to separate a sub-fraction; and obtaining a fraction having an A260/A280 value of a predetermined range from the sub-fraction, and non-diffusive botulinum toxin causing local muscle paralysis purified thereby. |
申请公布号 |
WO2011152618(A3) |
申请公布日期 |
2012.05.24 |
申请号 |
WO2011KR03547 |
申请日期 |
2011.05.13 |
申请人 |
MEDEXGEN INCORPORATED;CHUNG, YONG HOON;LEE, HYUN SUB |
发明人 |
CHUNG, YONG HOON;LEE, HYUN SUB |
分类号 |
A61K38/16;A61K35/74;A61P21/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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