发明名称 |
RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS |
摘要 |
The present invention is directed to nucleic acids delivery systems and methods of modulating an expression of a target gene using the same. In particular, the invention relates to nucleic acids conjugates containing an endosomal release-promoting moiety. The nucleic acids conjugates further contain a nuclear localization signal moiety, and/or a cell targeting moiety.
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申请公布号 |
US2011230420(A1) |
申请公布日期 |
2011.09.22 |
申请号 |
US200913129705 |
申请日期 |
2009.11.17 |
申请人 |
ENZON PHARMACEUTICALS, INC. |
发明人 |
ZHAO HONG;XIA JING;REDDY PRASANNA |
分类号 |
A61K38/14;A61P35/00;C07K9/00;C12N5/00 |
主分类号 |
A61K38/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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