METHODS OF APPLYING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THUASOLYL)-1,8-NAPHTHYDIRINE-3-CARBOXYLIC ACID FOR TREATMENT OF CANCER

摘要

FIELD: medicine. ^ SUBSTANCE: methods in accordance with invention relate to introduction of enantiomerically pure (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methyamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiasolyl)-1,8-naphthydirine-3-carboxylic acid in dose from 50 to 90 mg/m2 for treatment of myelogenous leukemia leukemia and in dose from 45 to 75 mg/m2 for treatment of ovary cancer. ^ EFFECT: extension of arsenal of medications for treatment of ovary cancer and myelogenous leukemia. ^ 37 cl, 15 tbl, 20 dwg, 11 ex