发明名称 METHOD OF COMPLEX IMMUNOMODULATING TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE WITH REDUCED LEFT VENTRICULAR EJECTION FRACTION
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, namely to cardiology, and deals with complex immunomodulating treatment of patients with chronic heart failure with reduced left ventricular heart ejection fraction. For this purpose in commonly accepted complex of drug therapy, which includes -adrenoblockers, ACE inhibitors, diuretics, cardiomagnyl, additionally introduced is recombinant human interleukin 2 (IL-2). IL-2 is introduced in dose 500 IU/ml, in 200 ml of physiological solution, which containf for stabilisation 10 ml of 5% albumin solution, intravenously drop-by-drop daily 1 time for 10 days; treatment course is repeated 1 time per 3 months during 12 months. ^ EFFECT: complex treatment ensures suppression of chronic immune inflammation due to ability of IL-2 in elaborated mode of introduction to reduce level of endogenic cytokins and activate T- and B- lymphocytes efficiently in said group of patients. ^ 2 ex, 2 tbl
申请公布号 RU2422136(C1) 申请公布日期 2011.06.27
申请号 RU20100107922 申请日期 2010.03.03
申请人 UCHREZHDENIE ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT KARDIOLOGII SIBIRSKOGO OTDELENIJA RAMN 发明人 TEPLJAKOV ALEKSANDR TROFIMOVICH;RYBAL'CHENKO ELENA VIKTOROVNA;BOLOTSKAJA LARISA ALEKSEEVNA
分类号 A61K31/138;A61K31/401;A61K31/433;A61K38/20;A61P9/10;A61P37/02 主分类号 A61K31/138
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