发明名称 METHOD OF STABILIZING PREPARATION
摘要 Disclosed is a method for stabilizing a solid pharmaceutical preparation containing a pharmacological substance and sodium lauryl sulfate, the method comprising incorporating into the preparation at least one member selected from the group consisting of neutral salts, basic salts and basic substances. The preparation containing sodium lauryl sulfate prepared by the method of the invention has superior performance, including high storage stability, suppression of discoloration and deterioration, and prevention of change in its properties, such as the dissolution rate of pharmacological substance from the preparation.
申请公布号 EP1300160(A4) 申请公布日期 2009.07.29
申请号 EP20010932213 申请日期 2001.05.23
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 TOMOHIRA, YUSO;MUKAI, TADASHI;KASHIMOTO, MINORU;NAGASAWA, MASAKAZU;ICHIBA, TETSUROH;KURIBAYASHI, DAISUKE;OKA, YOSHIKAZU;TOGUCHI, HAJIME
分类号 A61K9/20;A61K47/02;A61K47/20;(IPC1-7):A61K47/20;A61K47/12;A61K47/24 主分类号 A61K9/20
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