发明名称 Aryl alkyl carbamate derivatives production and use thereof in therapy
摘要 Disclosed are compounds of formula (I), wherein the substituents are as defined in the specification. The compounds can be prepared from compounds of formulae (Ia) and (V) by methods described herein. The compounds of formula (I) are FAAH enzyme inhibitors useful in the treatment of acute or chronic pain, dizziness, vomiting, nausea, eating disorders, neurological and psychiatric pathologies, acute or chronic neurodegenerative diseases, epilepsy, sleep disorders, cardiovascular diseases, renal ischaemia, cancers, disorders of the immune system, allergic diseases, parasitic, viral or bacterial infectious diseases, inflammatory diseases, osteoporosis, ocular conditions, pulmonary conditions, gastrointestinal diseases or urinary incontinence.
申请公布号 NZ541148(A) 申请公布日期 2009.01.31
申请号 NZ20040541148 申请日期 2004.01.22
申请人 SANOFI-AVENTIS 发明人 ABOUABDELLAH, AHMED;ALMARIO GARCIA, ANTONIO;HOORNAERT, CHRISTIAN;RAVET, ANTOINE
分类号 A61K31/27;A61K31/33;A61P1/00;A61P9/00;A61P11/00;A61P13/10;A61P25/00;A61P35/00;A61P37/08;C07C269/00;C07C269/06;C07C271/10;C07C271/12;C07C271/14;C07C271/16;C07C271/18;C07C271/20;C07D213/40;C07D215/12;C07D217/18;C07D241/12;C07D261/08;C07D263/44;C07D285/06;C07D307/91;C07D333/20;C07D333/58;(IPC1-7):C07C271/10 主分类号 A61K31/27
代理机构 代理人
主权项
地址