HISTOPHILUS SOMNI ANTIGENS, COMPOSITIONS AND METHODS OF USE

摘要

This invention provides, among other things, protein, polypeptides, and fragments thereof, derived from bacteria Histophilus somni. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto. Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments, variants and/or nucleic acids as well as detecting antibodies against the proteins, polypeptides, variants and fragments.