发明名称 PYRAZOLECARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The invention concerns N-piperidino-5-(4-bromophenyl)-1- (2,4dichlorophenyl)-4-ethylpyrazole-3-carboxamide of formula (I), (See formula I) the salts and solvents thereof which are powerful antagonists of cannabinoid CB 1 receptors. The method for preparing them consists in reacting a functional derivative of 5-(4- brothophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole-3-carboxylic acid with 1-aminopiperidine with subsequent optional salification.
申请公布号 CA2358885(C) 申请公布日期 2007.04.17
申请号 CA20002358885 申请日期 2000.01.28
申请人 SANOFI-SYNTHELABO 发明人 CAMUS, PHILIPPE;MARTINEZ, SERGE;RINALDI, MURIELLE;BARTH, FRANCIS
分类号 C07D231/14;A61K31/415;A61K31/454;A61P3/00;A61P3/04;A61P25/00;A61P25/18;A61P25/28;A61P25/32;A61P25/34;A61P43/00;C07C69/738;C07C251/80 主分类号 C07D231/14
代理机构 代理人
主权项
地址