THERAPEUTIC AGENT FOR ARTERIOSCLEROSIS

摘要

A prophylactic and/or therapeutic agent for arteriosclerosis comprising an antibody directed against platelet factor 4 (PF4) (an anti-PF4 antibody) as an active ingredient; an inhibitor of the calcification in the blood vessel and/or the calcification in an atherosclerotic plaque comprising an anti-PF4 antibody as an active ingredient; an inhibitor of the differentiation of an arterial smooth muscle cell into an osteoblast-like cell comprising an anti-PF4 antibody as an active ingredient; and a method for inhibiting the differentiation of an arterial smooth muscle cell into an osteoblast-like cell using an anti-PF4 antibody.