发明名称 |
Epothilone resistant cell lines |
摘要 |
Epothilone resistant cells lines are disclosed. The invention also discloses methods for identifying substances which are cytotoxic to epothilone resistant cells or which are chemosensitizers or analogs of epothilone. The invention further discloses methods for identifying epothiolone resistant cells and for inhibiting the growth of epothilone resistant cells in vitro and in vivo. The invetion also discloses antibodies specific for epothilone resistant cells. Also disclosed is a method to identify microtubule stabilizing agents using the epothilone resistant cell lines disclosed.
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申请公布号 |
US2004038324(A1) |
申请公布日期 |
2004.02.26 |
申请号 |
US20030432072 |
申请日期 |
2003.05.19 |
申请人 |
ATADJA PETER WISDOM.;WARTMANN MARKUS;YAN-NEALE YAN;COHEN DALIA |
发明人 |
ATADJA PETER WISDOM.;WARTMANN MARKUS;YAN-NEALE YAN;COHEN DALIA |
分类号 |
A61K39/395;A61K45/00;A61K47/48;A61P35/00;C07K16/18;C12N5/09;C12Q1/04;G01N33/15;G01N33/50;G01N33/53;G01N33/566;(IPC1-7):G01N33/574;C12N5/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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