发明名称 Piperazine mono(dithio)carbamate ester compounds and analogs thereof: preparation method and uses thereof
摘要 In accordance with the present invention, there is provided a new class of compounds, i.e., mono(dithio)carbamate esters of piperazine and analogs thereof, with or without substituents. Also provided are methods for the preparation of invention compounds and the pharmaceutical use thereof in the treatment of a variety of pathological conditions, especially for the treatment of cancers. A lead compound has shown good anticancer activity with low toxicity.
申请公布号 US2003149021(A1) 申请公布日期 2003.08.07
申请号 US20020157733 申请日期 2002.05.28
申请人 MEDINOX, INC. 发明人 LI RUNTAO;CHENG TIEMING;CUI JINGRONG;WANG TINGMIN
分类号 C07D215/22;C07D295/194;(IPC1-7):C07D279/12;C07D265/32;A61K31/55;A61K31/553;A61K31/554;A61K31/551;A61K31/54;A61K31/537;A61K31/495 主分类号 C07D215/22
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