| 发明名称 |
ANTISENSE MODULATION OF HORMONE-SENSITIVE LIPASE EXPRESSION |
| 摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating th e expression of hormone-sensitive lipase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acid s encoding hormone-sensitive lipase. Methods of using these compounds for modulation of hormone-sensitive lipase expression and for treatment of diseases associated with expression of hormone-sensitive lipase are provided .</p> |
| 申请公布号 |
CA2453894(A1) |
申请公布日期 |
2003.02.06 |
| 申请号 |
CA20022453894 |
申请日期 |
2002.07.15 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
WATT, ANDREW T.;BUTLER, MADELINE M.;FREIER, SUSAN M.;WYATT, JACQUELINE R. |
| 分类号 |
C12N15/09;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P35/00;C12N15/113;C12N15/55;(IPC1-7):C12Q1/68;C07H21/02;C07H21/04;A01N43/04;C12P19/34;C12N15/63;C12N15/86 |
主分类号 |
C12N15/09 |
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