发明名称 |
1,4,5,6-tetrahydropyrazolo-[3,4,-c]-pyridin-7-ones useful as factor Xa inhibitors |
摘要 |
The present application describes 1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-ones of the following formula or pharmaceutically acceptable salt forms thereof: wherein ring Rb is 3-amido or 4-methoxy, Ra can be cyano, trifluoromethyl, or amido, and R can be a substituted phenyl, a substituted imidazolyl, or a substituted pyridine. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
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申请公布号 |
US2002177713(A1) |
申请公布日期 |
2002.11.28 |
申请号 |
US20020124383 |
申请日期 |
2002.04.17 |
申请人 |
PINTO DONALD JOSEPH PHILIP;GALEMMO ROBERT ANTHONY;ORWAT MICHAEL JAMES;QUAN MIMI LIFEN |
发明人 |
PINTO DONALD JOSEPH PHILIP;GALEMMO ROBERT ANTHONY;ORWAT MICHAEL JAMES;QUAN MIMI LIFEN |
分类号 |
A61P7/02;C07D471/04;(IPC1-7):C07D471/02;A61K31/474 |
主分类号 |
A61P7/02 |
代理机构 |
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地址 |
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