发明名称 |
3,4-DISUBSTITUTED PHENYLETHANOLAMINOTETRALINCARBOXAMIDE DERIVATIVES |
摘要 |
3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives represented by general formula (I) and their pharmacologically acceptable salts having a selective .beta.2-adrenergic receptor stimulating effect with a relieved burden on the heart such as frequent pulse. In said formula, A represents lower alkylene; B represents amino, di(lower alkyl)amino or 3- to 7membered alicyclic amino optionally containing oxygen in the ring; n is an integer of 1 or 2; the carbon atom marked with "*" means a carbon atom or the R- or S- configuration or a mixture thereof; and the carbon atom marked with "(S)" means a carbon atom of the S-configuration. These compounds are useful as a preventive for threatened abortion/premature birth, a bronchodilator and a pain-relieving and lithagogue agent in ureterolithiasis.
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申请公布号 |
CA2245490(A1) |
申请公布日期 |
1997.08.21 |
申请号 |
CA19972245490 |
申请日期 |
1997.02.18 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
MURANAKA, HIDEYUKI;TANAKA, NOBUYUKI;KOBAYASHI, HIROAKI;SAITO, MASARU;KITAZAWA, MAKIO;TAMAI, TETSURO;OKAZAKI, KOSUKE;KIKUCHI, KEN |
分类号 |
C07C235/06;C07D295/185;(IPC1-7):C07C235/20;A61K31/16 |
主分类号 |
C07C235/06 |
代理机构 |
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