| 摘要 |
<p>Lupane derivatives of general formula (I) in which R is a radical of general formula (II) for which R' is a hydrogen atom or an alkyl radical, X is carbamoyl, N-méthyl carbamoyl, aminocarbonyl or N-methylaminocarbonyl, Y is substituted phenylene of general formula (III), in which R1 and R2 are H, halogen, alkyl, alkyloxy or nitro, provided that both are not H, R° and R°°, which are the same or different, are hydrogen atoms or alkyl radicals and n is 6 to 12, m is 0 to 2 and p is 0 to 2, with: 6 < m+n+p < 12, the alkyl radicals (1 to 4C) being straight or branched. The invention also concerns the salts of said derivatives when they exist and their preparation. The products according to the invention are especially useful in the treatment of AIDS and in infections induced by the herpes family of viruses.</p> |
