发明名称 CARTILAGE-DERIVED LEUKOCYTE ELASTASE-INHIBITOR
摘要 A protein or a pharmaceutically acceptable salt thereof. The protein has a molecular weight of 10,000-30,000 Dalton, an isoelectric point greater than 9.5, and an N terminus of the sequence H-Lys-X-Phe-Lys-Val-Asp-Val-Leu-Ala-Ala-Leu-X-Phe-Asn-Ala-, wherein X is an amino acid or a tryptic cleavage product which has the sequence -Gly-Ala-Asn-Ala-Val-Asn-. Methods for the isolation and purification of the protein, compositions containing the protein, and methods for the use of the protein and compositions, are also disclosed.
申请公布号 AU7624287(A) 申请公布日期 1988.02.11
申请号 AU19870076242 申请日期 1987.07.29
申请人 HOECHST A.G., RUSH-PRESBYTERIAN-ST LUKE'S MEDICAL CENTER 发明人 KLAUS E. KUETTNER;MICHAEL T. DIMUZIO;DIETRICH BROCKS;DOMINIQUE TRIPIER
分类号 A61K38/55;A61K38/00;A61P7/02;A61P9/10;A61P11/00;A61P13/02;A61P15/00;A61P17/00;A61P29/00;A61P35/00;A61P35/02;C07K14/00;C07K14/81;C12N9/99;C12P21/06 主分类号 A61K38/55
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