发明名称 METHOD FOR GENE INTRODUCTION INTO TARGET CELLS BY RETROVIRUS
摘要 <p>A method for elevating the gene introduction efficiency into target cells by a retrovirus which comprises infecting the target cells with the retrovirus in the presence of a mixture of an effective amount of a functional substance having a retrovirus-binding site with an effective amount of another functional substance having a target cell-binding site, or in the presence of an effective amount of a functional substance having both of these binding sites in a single molecule. The functional substances are optionally immobilized on beads, etc. This method is usable in, for example, gene therapy.</p>
申请公布号 WO9718318(A1) 申请公布日期 1997.05.22
申请号 WO1996JP03254 申请日期 1996.11.07
申请人 TAKARA SHUZO CO., LTD.;ASADA, KIYOZO;UEMORI, TAKASHI;UENO, TAKASHI;KOYAMA, NOBUTO;HASHINO, KIMIKAZU;KATO, IKUNOSHIU 发明人 ASADA, KIYOZO;UEMORI, TAKASHI;UENO, TAKASHI;KOYAMA, NOBUTO;HASHINO, KIMIKAZU;KATO, IKUNOSHIU
分类号 A61K48/00;C07K14/505;C07K14/78;C12N9/10;C12N15/12;C12N15/867;(IPC1-7):C12N15/86;C12N5/10 主分类号 A61K48/00
代理机构 代理人
主权项
地址