发明名称 |
METHOD FOR INCREASING EXPRESSION YIELD OF A PROTEIN OF INTEREST |
摘要 |
The present invention relates to a method of producing a protein of interest comprising: (a) cultivating a mutant cell under conditions conducive for production of the protein wherein the mutant has a reduced or no expression of an endogenous polypeptide shown in SEQ ID NO: 2 compared to a parent host cell grown under the same conditions; and optionally (b) recovering the protein of interest. |
申请公布号 |
EP2247609(A1) |
申请公布日期 |
2010.11.10 |
申请号 |
EP20090713900 |
申请日期 |
2009.02.20 |
申请人 |
NOVOZYMES A/S |
发明人 |
HANSEN, MOGENS TRIER;RAVN, BIRTHE MARIE;DE MARIA, LEONARDO |
分类号 |
C07K14/38;C12P21/02 |
主分类号 |
C07K14/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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