| 发明名称 |
METHODS AND INTERMEDIATES FOR PREPARING PHARMACEUTICAL AGENTS |
| 摘要 |
Methods and intermediates useful for preparing a compound of formula I:;;and salts thereof. |
| 申请公布号 |
US2014364602(A1) |
申请公布日期 |
2014.12.11 |
| 申请号 |
US201314372995 |
申请日期 |
2013.02.01 |
| 申请人 |
Gilead Sciences, Inc. |
发明人 |
Cullen Aaron J.;Yu Richard Hung Chiu |
| 分类号 |
C07D417/12;C07C271/20;C07C309/73;C07D233/60;C07D277/24;C07D203/20;C07C329/16 |
主分类号 |
C07D417/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound selected from: wherein: R1a and R1b are each independently an amine protecting group; or R1a is an amine protecting group and R1b is H; R1c is —C(O)O(C1-C6)alkyl wherein —C(O)O(C1-C6)alkyl is optionally substituted with one or more halogen or (C1-C6)alkoxy; R2 is —SMe or imidazol-1-yl; and R4 is —SO2(C1-C6)alkyl or —SO2aryl, wherein —SO2(C1-C6)alkyl is optionally substituted with one or more halogen, and wherein —SO2aryl is optionally substituted with one or more halogen, (C1-C6)alkyl or NO2; and salts thereof; provided the compound is not: |
| 地址 |
Foster City CA US |
