发明名称 |
POROUS SILICON DRUG-ELUTING PARTICLES |
摘要 |
The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug-eluting particle for releasing therapeutic agents |
申请公布号 |
EP2427179(A4) |
申请公布日期 |
2013.09.11 |
申请号 |
EP20100772695 |
申请日期 |
2010.05.04 |
申请人 |
PSIVIDA US, INC. |
发明人 |
ASHTON, PAUL;GUO, HONG;CHEN, JIANBING;CANHAM, LEIGH |
分类号 |
A61K9/22;A61K9/20;A61K9/32;A61K47/30 |
主分类号 |
A61K9/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|