发明名称 Metal complexes of N-heterocyclic carbenes as antibiotics
摘要 A method for inhibiting microbial growth comprises administering an effective amount of a silver complex of a N-heterocyclic amine. A method for treating cancer cells or a method for imaging one or more tissues of a patient includes administering an effective amount of a complex of a N-heterocyclic amine and a radioactive metal. A method for treating urinary tract infections utilizing silver complexes of N-heterocyclic carbenes. N-heterocyclic carbenes of the present invention may be represented by the formula wherein Z is a heterocyclic group, and R1 and R2 are, independently or in combination, hydrogen or a C1-C12 organic group selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, arylalkyl, alkylaryl, heterocyclic, and alkoxy groups and substituted derivatives thereof.
申请公布号 US8519146(B2) 申请公布日期 2013.08.27
申请号 US20060482410 申请日期 2006.07.07
申请人 YOUNGS WILEY J.;TESSIER CLAIRE A.;GARRISON JERED;QUEZADA CAROL;MELAIYE ABDULKAREEM;PANZNER MATTHEW;DURMUS SEMIH;THE UNIVERSITY OF AKRON 发明人 YOUNGS WILEY J.;TESSIER CLAIRE A.;GARRISON JERED;QUEZADA CAROL;MELAIYE ABDULKAREEM;PANZNER MATTHEW;DURMUS SEMIH
分类号 C07F15/00;C07F1/00 主分类号 C07F15/00
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