发明名称 SODIUM LAQUINIMOD CRYSTALS AND METHOD FOR MAKING THEREOF
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to a mixture of sodium laquinimod crystal particles wherein 10% or more of total volume of sodium laquinimod particles are sized more than 40 micron. Also, the invention refers to the mixture of sodium laquinimod crystal particles of tap density at least 0.6 g/ml, to a pharmaceutical composition, to a composition, to a method of sodium laquinimod recrystallisation, as well as to a method for preparing the pharmaceutical composition. ^ EFFECT: preparation of the new biologically active compounds used for treatment of disease caused by autoimmune or pathological inflammation. ^ 39 cl, 17 ex, 5 tbl, 3 dwg
申请公布号 RU2415841(C2) 申请公布日期 2011.04.10
申请号 RU20080119456 申请日期 2006.10.18
申请人 TEVA FARMAS'JUTIKAL INDASTRIZ, LTD. 发明人 FRENKEL ANTON;GUREVICH EHDUARD;LAKSER AVITAL
分类号 A61K31/4704;A61P29/00;A61P37/02;C07D215/22 主分类号 A61K31/4704
代理机构 代理人
主权项
地址