发明名称 |
COMPLEXES OF TRPC DOMAINS AND SESTD1 DOMAINS AND METHODS AND USES INVOLVING THE SAME |
摘要 |
The present invention relates to an isolated complex comprising a first protein comprising or consisting of a classical transient receptor potential channel (TRPC) or a functionally active variant thereof and a second protein comprising or consisting of the first spectrin (Spec 1) domain of SEC14 and spectrin domains 1, a test system comprising the first protein and the second protein as well as means for detecting interaction of the first and the second protein, a method for screening for a TRPC modulator using the system and the use of the test system for the identification of a TRPC modulator.
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申请公布号 |
KR20100076992(A) |
申请公布日期 |
2010.07.06 |
申请号 |
KR20107009065 |
申请日期 |
2008.10.14 |
申请人 |
SANOFI-AVENTIS |
发明人 |
MIEHE SUSANNE;STRUEBING CARSTEN |
分类号 |
C07K19/00;C07K14/47;G01N33/15;G01N33/68 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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