发明名称 |
HIV-CHEMOKINE |
摘要 |
Disclosed is a novel gene comprising an open reading frame encoded on the plus strand of the pro-viral DNA, and located in the region of HIV-1 long terminal repeat. The gene encodes a protein that is related to, and has a structural motif resembling that of chemokine proteins. Depending upon the ribosomal frameshift, a plurality of proteins may be translated from the antisense RNA. The protein has similarity with chemokine SDF-1 and may play a role as a cofactor with gp120 in the binding to and entry of HIV to a target cell. |
申请公布号 |
DE69933993(D1) |
申请公布日期 |
2006.12.28 |
申请号 |
DE1999633993 |
申请日期 |
1999.02.12 |
申请人 |
LUDWIG, LINDA BESANTE |
发明人 |
LUDWIG, B.;AMBRUS, L.;KRAWCZYK, ANNE |
分类号 |
C12N1/00;C12N15/09;A61K38/00;A61K39/00;A61K39/21;A61K48/00;A61P37/04;C07K14/155;C07K14/16;C12N15/49 |
主分类号 |
C12N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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