发明名称 |
Rapid methods for identifying modifiers of cellular apoptosis activity |
摘要 |
The invention provides a single-well, microscale method of determining the specific apoptotic activity of a cell. The method consists of contacting a cell population of about 1x105 cells for a time period of between about 30 minutes and 4 hours with a sufficient volume of medium containing an apoptotic specific diagnostic reagent and a diagnostic accessory reagent so as to cover the cell population, and determining the activity of the apoptotic specific diagnostic reagent. The invention also provides a method of identifying a compound which induces apoptosis. The invention further provides a rapid method of identifying a compound which inhibits apoptosis.
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申请公布号 |
US6518032(B1) |
申请公布日期 |
2003.02.11 |
申请号 |
US19990300374 |
申请日期 |
1999.04.27 |
申请人 |
IDUN PHARMACEUTICALS, INC. |
发明人 |
FRITZ LAWRENCE C.;DIAZ JOSE-LUIS;ARMSTRONG ROBERT C.;TOMASELLI KEVIN J. |
分类号 |
C12N15/09;C12Q1/06;G01N33/15;G01N33/50;(IPC1-7):C12Q1/00;C12Q1/02;C12Q1/18;C12Q1/37 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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