The invention relates to the field of cancer therapy and diagnosis, in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promotor or functional fragment thereof allowing for expression of a nucleic acid of interest operably linked to said promotor or functional fragment thereof in a cancer cell wherein said expression in said cancer cell is essentially carcinoma selective.
申请公布号
EP1190085(A2)
申请公布日期
2002.03.27
申请号
EP20010952047
申请日期
2001.02.28
申请人
SYNVOLUX IP B.V.
发明人
DE LEIJ, LOU, FRANCISCUS, MARIA, HUBERTUS;RUITERS, MARCEL, HERMAN, JOSEF;MCLAUGHLIN, PAMELA, MARIJKE, JANE;HARMSEN, MARTIN, CONRAD;VAN DER MOLEN, HENK;TERPSTRA, PETER;DOKTER, WILLEM, HENDRIK, ABRAHAM