IMPROVEMENT TO THE EXCHANGE AND RELEASE OF AN AMINE FROM ITS CARBAMOYL FLUORIDE

摘要

The invention concerns a method for treating an aryl carbamoyl fluoride, comprising in its molecule at least a perhalogenated aliphatic carbon, which bears at least a halogen atom to be exchanged with the fluorine. The method comprises a step which consists in contacting said carbamoyl fluoride with hydrofluoric acid, the hydrofluoric acid/carbamoyl fluoride ratio being maintained during the reaction at a value less than 4, preferably 5. The invention is characterised in that said ratio is not more than 11. The invention is applicable to organic synthesis.