发明名称 |
Thioalkyl alpha substituted pyrimidine compounds |
摘要 |
The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I and pyrimidine-thioalkyl and alkylethers of Formula I, where R4 is selected from the group consisting of -H or -NR15R16 where R15 is -H and R16 is -H, C1-C6 alkyl, -NH2 or R15 and R16 taken together with the -N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R6 is -S-C1-6 alkyl (preferably -SCH3); The compounds of Formula I are useful in the treatment of individuals who are HIV positive. |
申请公布号 |
AU2305099(A) |
申请公布日期 |
1999.05.03 |
申请号 |
AU19990023050 |
申请日期 |
1998.09.21 |
申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
JOEL MORRIS;DONN G WISHKA;WADE J. ADAMS;JANICE M. FRIIS |
分类号 |
C07D239/58;A61K31/505;A61K31/506;A61K31/5377;A61P31/18;C07D239/26;C07D239/56;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D491/04;C07D491/048 |
主分类号 |
C07D239/58 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|