发明名称 |
Treatment of central nervous system disorders with imidazole angiotensin-II receptor antagonists |
摘要 |
<p>Substituted imidazoles such as 2-butyl-4-chloro-1-Ä(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylÜ-5-(hyd roxymethyl)imidazole and 2-butyl-4-chloro-1-Ä(2'-carboxybiphenyl-4-yl)methylÜ-5-(hydroxymethyl) imidazole and pharmaceutically acceptable salts thereof are useful for treating central nervous system disorders, such as cognitive and learning disorders, mediated by angiotensin II.</p> |
申请公布号 |
EP0803252(A2) |
申请公布日期 |
1997.10.29 |
申请号 |
EP19960120135 |
申请日期 |
1991.02.14 |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
CHIU, ANDREW TAK-CHAU;DE NOBLE, VICTOR JOHN;DUNCIA, JOHN JONAS VYTAUTAS;WONG, PANCRAS CHOR BUN |
分类号 |
A61K31/41;A61K31/415;A61K31/4174;A61K31/4178;A61K31/495;A61K31/675;A61P25/28;A61P43/00;C07D233/56;C07D233/60;C07D233/61;C07D403/10;(IPC1-7):A61K31/415 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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