| 发明名称 |
Self-assembled, defective, non-self-propagating lentivirus particles |
| 摘要 |
Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective nonself-propagating viral particles are disclosed. The viral vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and drugs.
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| 申请公布号 |
US5614404(A) |
申请公布日期 |
1997.03.25 |
| 申请号 |
US19920995923 |
申请日期 |
1992.12.21 |
| 申请人 |
THERIOD BIOLOGICS, INCORPORATED |
发明人 |
MAZZARA, GAIL P.;ROBERTS, BRYAN;PANICALI, DENNIS L.;STALLARD, VIRGINIA;GRITZ, LINDA R.;MAHE, ANNA |
| 分类号 |
A61K9/50;A61K38/00;A61K39/00;A61K47/48;C07K14/105;C07K14/155;C07K14/16;C12N7/04;C12N9/12;C12N9/22;C12N9/50;C12N15/863;C12N15/88;G01N33/569;(IPC1-7):C12N15/86;C12N15/63;A61K39/21 |
主分类号 |
A61K9/50 |
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