发明名称 Benzene derivatives, their preparation and pharmaceutical compositions in which they are present
摘要 The present invention relates to compounds of the formula <IMAGE> (I) in which: R1 is hydrogen or a halogen atom; R2 is a cyclohexyl or a phenyl; R3 is a (C3-C6) cycloalkyl; R4 is hydrogen, (C1-C6) alkyl or a (C3-C6) cycloalkyl; A is -CO-CH2-, -CH(Cl)-CH2-, -CH(OH)-CH2-, CH2-CH2-, -CH=CH- and -C 3BOND C-, or their addition salts with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.
申请公布号 US5449693(A) 申请公布日期 1995.09.12
申请号 US19940264064 申请日期 1994.06.22
申请人 SANOFI 发明人 BRELIERE, JEAN-CLAUDE;CASELLAS, PIERRE;LAVASTRE, SERGE;PAUL, RAYMOND
分类号 A61K31/135;A61P37/06;C07C209/68;C07C209/70;C07C209/74;C07C211/27;C07C211/28;C07C211/29;C07C211/35;C07C213/00;C07C215/28;C07C215/30;C07C215/38;C07C221/00;C07C225/16;C07C225/18;(IPC1-7):A61K31/135 主分类号 A61K31/135
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