发明名称 |
FIBROBLAST GROWTH FACTOR (FGF)-BASED STABILIZED COMPOSITIONS AND THE USE THEREOF |
摘要 |
A novel stabilized composition is provided herein. The stabilized compositi on includes an agent having a cell and tissue regenerating activity. The agent comprises at least one functionalized, substituted dextran containing the following functions, namely carboxymethyl, benzylamide or benzylamide sulphonate, in association with at least one of the following: an acid FGF; a basic FGF; a derivative thereof; an analogu e thereof; a fragment thereof, the fragment thereof having a biological activity. The agent is capable of at least partially restoring the biological activity of the acid and/or basic FGF/FGFs which have been inactivated by prolonged storage or temperature. Novel uses for this stabilized composition are also provided.
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申请公布号 |
CA2048638(A1) |
申请公布日期 |
1990.09.10 |
申请号 |
CA19902048638 |
申请日期 |
1990.03.09 |
申请人 |
THERAPEUTIQUES SUBSTITUTIVES |
发明人 |
BARRITAULT, DENIS;JOZEFONVICZ, JACQUELINE;SLAOUI, FAOUZI;TARDIEU, MICHELE;CARUELLE, JEAN-PIERRE;COURTY, JOSE |
分类号 |
A61K9/06;A61K9/00;A61K9/12;A61K9/127;A61K31/70;A61K38/18;A61K38/27;A61K47/36;A61L15/44;A61P43/00;C08B37/00;(IPC1-7):A61K38/18;A61K31/715 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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