发明名称 ENKEPHALIN DERIVATIVES
摘要 <p>M-1062-C1 Novel analgesic and antipsychotic agents having the formula wherein Q is in which R1 is hydrogen, hydroxy or halogen and R4 is hydrogen or, R, and R4 are both hydroxy; Z is hydrogen or straight chain lower alkyl having from 1 to 4 carbon atoms and X is methylene, carbonyl, hydroxymethylene, thio, sulvinyl or sulfonyl, or Z and X, taken together, are methylidenyl, with the proviso that when X is sulfonyl or sulfinyl, Z is other than hydrogen; R5 is hydrogen or halogen, and R2 is H, a straight or branched lower alkyl group having from 1 to 4 carbon atoms, the group or the group wherein R3 is hydroxy, amino, alkylamino or dialkylamino wherein the alkyl moiety is straight or branched and has from 1 to 4 carbon atoms, diastereomers, enantiomers and pharmaceutically acceptable salts thereof.</p>
申请公布号 CA1179348(A) 申请公布日期 1984.12.11
申请号 CA19830441921 申请日期 1983.11.24
申请人 MERRELL PHARMACEUTICALS INC. 发明人 CARR, ALBERT A.;FARR, ROBERT A.;KANE, JOHN M.
分类号 C07D241/08;(IPC1-7):C07D241/08 主分类号 C07D241/08
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