主权项 |
1. A compound of formula I wherein A is R1 is selected from aryl or heteroaryl, R2 is selected from hydrogen or C1-7 alkyl, R3 is selected from hydrogen or C1-7 alkyl, R4 is selected from hydrogen, C1-7 alkyl, C1-7 alkoxy or C(O)NR′R″, R5 is selected from C1-7 alkyl, C3-8 cycloalkyl, C1-7 haloalkyl, cyano, C1-7 hydroxyalkyl or C(O)NR′R″, R6 is selected from hydrogen, C1-7 alkyl or C1-7 hydroxyalkyl, or R5 and R6 form together C3-8 cycloalkyl, R′ and R″ are in each occurrence independently selected from hydrogen or C1-7 alkyl, X and Y are independently selected from C or N, with the proviso that X and Y are not simultaneously N, Z is selected from CH or N, B is selected from C1-C4-alkylene, C2-C4-alkenylene, C2-C4-alkynylene or —O—C1-C4-alkyl. |