发明名称 |
PEPTIDE SEQUENCE DESIGN AND USE THEREOF FOR PEPTIDE-MEDIATED SIRNA DELIVERY |
摘要 |
<p>The invention provides, in one aspect, peptides and a complex comprising one of the peptides and a cargo molecule, wherein the peptide and the cargo molecule are coupled by non-covalently. The peptides of the invention were found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets.</p> |
申请公布号 |
EP2782926(A1) |
申请公布日期 |
2014.10.01 |
申请号 |
EP20120852395 |
申请日期 |
2012.11.23 |
申请人 |
POSITEC POWER TOOLS (SUZHOU) CO., LTD;CHEN, PU |
发明人 |
CHEN, PU;JAFARI, MOUSA;XU, WEN;CHEN, BAOLING;PAN, RAN;KARUNARATNE, NEDRA |
分类号 |
C07K14/00;A61K9/00;A61K9/08;A61K31/713;A61K38/00;A61K47/12;A61K47/48;A61P35/00;C07K7/06;C07K7/08;C07K14/47;C07K19/00;C12N15/11;C12N15/113;C12N15/87 |
主分类号 |
C07K14/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|