发明名称 |
COMPOSITIONS AND METHODS FOR ENHANCEMENT OF NUCLEIC ACID DELIVERY |
摘要 |
Embodiments of the invention include devices and methods for delivery of nucleic acids as active agents. Embodiments of the invention include devices and methods for delivery of nucleic acids as active agents. In an embodiment, an article for delivering an active agent is included. The article can include a dehydrated complex including a nucleic acid, a transfection agent, and a saccharide protectant. The nucleic acid and transfection agent can form a liposome or a lipoplex. The dehydrated complex can be disposed within a polymeric matrix. The dehydrated complex can be disposed within a microparticle. Other embodiments are also included herein.
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申请公布号 |
CA2800679(A1) |
申请公布日期 |
2012.01.12 |
申请号 |
CA20112800679 |
申请日期 |
2011.06.29 |
申请人 |
SURMODICS, INC. |
发明人 |
MCGONIGLE, JOSEPH SCHMIDT;SLAGER, JORAM |
分类号 |
A61K9/127;A61K9/16;A61K9/19;A61K47/36;A61K47/48;A61K48/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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