ANTIBODY BINDING BOTH BCMA AND TACI

摘要

PROBLEM TO BE SOLVED: To provide a composition for inhibiting proliferation of tumor cells. SOLUTION: Molecules that interfere with the binding of a tumor necrosis factor receptor with its ligand, such as a soluble receptor or an anti-receptor antibody, have proven usefulness in both basic research and as therapeutics. The invention provides antibodies that bind two tumor necrosis factor receptor family members, i.e. the transmembrane activator and calcium modulator and cyclophilin ligand-interactor (TACI) receptor, and the B-cell maturation (BCMA) receptor. COPYRIGHT: (C)2011,JPO&INPIT