发明名称 |
Methods for monitoring drug activities in vivo |
摘要 |
Methods, systems and equipment useful for monitoring in vivo activities of CCI-779 or other drugs. Numerous drug activity genes can be identified by the present invention. The expression profiles of these genes in peripheral blood mononuclear cells are modulatable by CCI-779 or other drugs. Therefore, these genes can be used as surrogate markers for detecting or monitoring drug activities in vivo.
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申请公布号 |
US7643943(B2) |
申请公布日期 |
2010.01.05 |
申请号 |
US20040793032 |
申请日期 |
2004.03.05 |
申请人 |
WYETH LLC |
发明人 |
BURCZYNSKI MICHAEL E.;BONI JOSEPH;DORNER ANDREW J.;TWINE NATALIE C.;STOVER JENNIFER;TREPICCHIO WILLIAM L.;FITZPATRICK VIRGINIA;IMMERMANN FRED |
分类号 |
G01N33/48;A61K38/17;C07K16/18;C12N;C12Q1/68;G01N33/53;G01N33/567 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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