The invention provides novel methods for designing and administering therapeutic treatments for subjects afflicted with cancer. One aspect provides methods of identifying activated RTK pathways in a cancer and formulating treatment plans based on a plurality of RTK inhibitors. The invention further provides methods for evaluating candidate tyrosine kinase inhibitors for therapeutic efficacy.
申请公布号
WO2008127707(A1)
申请公布日期
2008.10.23
申请号
WO2008US04801
申请日期
2008.04.11
申请人
DANA FARBER CANCER INSTITUTE;DEPINHO, RONALD, A.;STOMMEL, JAYNE, M.