发明名称 |
CYTOCHROME C PROTEIN AND ASSAY |
摘要 |
The present invention relates to a a cytochrome c-reporter fusion protein construct comprising a modified cytochrome c protein which targets the mitochondria and has a reduced ability to induce apoptosis in a living cell. The invention also relates to nucleic acid constructs encoding such protein fusions and cells stably transfected with such constructs. The stably transfected cells of the invention can be used in assays to detect apoptosis .
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申请公布号 |
CA2549523(A1) |
申请公布日期 |
2005.06.30 |
申请号 |
CA20042549523 |
申请日期 |
2004.12.17 |
申请人 |
GE HEALTHCARE UK LIMITED |
发明人 |
ISMAIL, RAHMAN AZIZ;CUSHING, ADRIAN;FRANCIS, MICHAEL JOHN;STUBBS, SIMON LAURENCE JOHN |
分类号 |
C07K14/80;C12N5/10;C12N15/67;G01N33/50 |
主分类号 |
C07K14/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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