发明名称 NOVEL HAIRPIN POLYAMIDE
摘要 It is intended to provide a pyrrole-imidazole polyamide type functional molecule having enhanced abilities of alkylating DNA and recognizing a sequence, compared with the existing functional molecules of this type, for a specific base sequence occurring on DNA. A hairpin polyamide having an alkylation site via a vinyl linker at the end of a pyrrole-imidazole polyamide. Drugs for inhibiting the expression of a specific gene and anticancer agents containing the above hairpin polyamide.
申请公布号 WO03076412(A1) 申请公布日期 2003.09.18
申请号 WO2003JP02423 申请日期 2003.03.03
申请人 JAPAN SCIENCE AND TECHNOLOGY CORPORATION;SUGIYAMA, HIROSHI;BANDO, TOSHIKAZU;SAITO, ISAO 发明人 SUGIYAMA, HIROSHI;BANDO, TOSHIKAZU;SAITO, ISAO
分类号 C12N15/09;A61K31/4178;A61P35/00;A61P43/00;C07D233/90;C07D403/14;C07D487/04;C07D487/10;(IPC1-7):C07D233/90;A61K31/417 主分类号 C12N15/09
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