发明名称 Pyrrolidine derivatives
摘要 The present invention relates to pyrrolidine derivatives and dimeric forms and/or pharmaceutically acceptable esters, and/or salts thereof. The compounds are useful as inhibitors of metalloproteases, e.g. zinc proteases, particularly zinc hydrolases, and which are effective in treating disease states are associated with vasoconstriction of increasing occurrences.
申请公布号 US6541638(B2) 申请公布日期 2003.04.01
申请号 US20010907135 申请日期 2001.07.17
申请人 HOFFMAN-LA ROCHE INC. 发明人 AEBI JOHANNES;BLUM DENISE;BUR DANIEL;CHUCHOLOWSKI ALEXANDER;DEHMLOW HENRIETTA;KITAS ERIC ARGIRIOS;LOEFFLER BERND MICHAEL;OBST ULRIKE;WALLBAUM SABINE
分类号 A61K31/40;A61K31/41;A61K31/4245;A61K31/454;A61P1/00;A61P3/10;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/06;A61P13/12;A61P15/08;A61P17/02;A61P25/28;A61P27/00;A61P27/06;A61P31/00;A61P35/00;A61P37/06;A61P39/06;A61P43/00;C07D207/12;C07D207/16;C07D207/48;C07D401/06;C07D401/12;C07D403/12;C07D409/12;C07D413/12;(IPC1-7):A61K31/454;A61K31/402;C07D403/06 主分类号 A61K31/40
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